p-Dichlorobenzyl
C8H8cL2
Alpha'-Dichloro-p-xylene
CAS number: 623-25-6
Molecular weight: 175.06
Other names: p-Diphenylmethyl chloride
Dichloro-p-xylene
1,4-Bis(chloromethyl)benzene
p-Dichlorobenzyl is a white crystalline solid with the CAS number 623-25-6, a melting point of 98-102°C, and a boiling point of 254°C. As an organic synthesis intermediate, it is primarily used in the preparation of compounds such as p-terephthalic alcohol and p-terephthalaldehyde, and can also be used as a crosslinking agent in the production of polysulfone nanofiltration membranes. In the materials field, it is used in the synthesis of new phenolic resins for applications in avionics and wear-resistant materials. In the pharmaceutical industry, it is used as an intermediate in the synthesis of loxoprofen sodium and methothrin, simplifying the pharmaceutical process. 1,4-(p-Dichlorobenzyl)chloride, also known as p-xylylenedichloride or 1,4-bis(chloromethyl)benzene, is an organic compound with the molecular formula C8H8Cl2 and a molecular weight of 175.06. It typically occurs as small white flaky crystals with specific physical properties. 1,4-(p-Dichlorobenzyl)chloride readily decomposes in water but has a moderate solubility in methanol (50 mg/mL). It is primarily prepared by photochlorination of p-xylene. This process requires precise control of reaction conditions to ensure product purity and yield. The prepared 1,4-(p-Dichlorobenzyl)chloride must be kept dry and at room temperature during storage to avoid unwanted chemical reactions.
1,4-(p-Dichlorobenzyl)chloride plays a crucial role in organic synthesis and is widely used as an intermediate in the synthesis of various compounds. One of its most notable applications is in the synthesis of p-phenylenediol (p-phenylenediol). p-phenylenediol is an important organic chemical with a wide range of applications in dyes, pharmaceuticals, pesticides, and other fields. Further conversion of 1,4-(p-Dichlorobenzyl)chloride allows for the efficient synthesis of terephthalic alcohol, thus meeting the needs of related industries. Furthermore, 1,4-(p-Dichlorobenzyl)chloride can be used to synthesize other organic compounds, such as terephthalic dimethyl ether and terephthalaldehyde. These compounds also have important applications in their respective fields, such as as dye intermediates and raw materials for pharmaceutical synthesis.
